Biophysical Tools to Study Cellular Mechanotransduction
نویسندگان
چکیده
منابع مشابه
Biophysical Tools to Study Cellular Mechanotransduction
The cell membrane is the interface that volumetrically isolates cellular components from the cell's environment. Proteins embedded within and on the membrane have varied biological functions: reception of external biochemical signals, as membrane channels, amplification and regulation of chemical signals through secondary messenger molecules, controlled exocytosis, endocytosis, phagocytosis, or...
متن کاملTools to study cell mechanics and mechanotransduction.
Analysis of how cells sense and respond to mechanical stress has been limited by the availability of techniques that can apply controlled mechanical forces to living cells while simultaneously measuring changes in cell and molecular distortion, as well as alterations of intracellular biochemistry. We have confronted this challenge by developing new engineering methods to measure and manipulate ...
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Cell-cell adhesions serve to mechanically couple cells, allowing for long-range transmission of forces across cells in development, disease, and homeostasis. Recent work has shown that such contacts also play a role in transducing mechanical cues into a wide variety of cellular behaviors important to tissue function. As such, understanding the mechanical regulation of cells through their adhesi...
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Physical forces, such as those due to gravity, are fundamental regulators of tissue development. To influence morphogenesis, mechanical forces must alter growth and function. Yet little is known about how cells convert mechanical signals into a chemical response. This presentation attempts to place the potential molecular mediators of mechanotransduction within the context of the structural com...
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triplet excitons of the guests by restricting their molecular motion at room temperature and preventing them from exposure to detrimental species such as oxygen and moisture 7–10. The formation of the long-lived triplet excitons of A through efficient energy transfer from the T 1 state of D allows for effective accumulation of excitons in the T 1 state of A on irradiation of the composite films...
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ژورنال
عنوان ژورنال: Bioengineering
سال: 2017
ISSN: 2306-5354
DOI: 10.3390/bioengineering4010012